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NDEL1 抗体 (AA 178-213)

NDEL1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50842 unconjugated
产品编号 ABIN6244172
发货至: 中国
  • 抗原 See all NDEL1 抗体
    NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))
    抗原表位
    • 22
    • 15
    • 15
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 178-213
    适用
    • 64
    • 52
    • 45
    • 2
    • 1
    人, 小鼠
    宿主
    • 86
    • 3
    • 1
    克隆类型
    • 78
    • 12
    多克隆
    标记
    • 20
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    This NDEL1 antibody is un-conjugated
    应用范围
    • 52
    • 52
    • 44
    • 20
    • 14
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    C, Pr, Rb, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This NDEL1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 178-213 amino acids from the Central region of human NDEL1.
    克隆位点
    RB50842
    亚型
    Ig Fraction
    Top Product
    Discover our top product NDEL1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))
    别名
    NDEL1 (NDEL1 产品)
    别名
    EOPA antibody, MITAP1 antibody, NDE1L1 antibody, NDE2 antibody, NUDEL antibody, NUDE2 antibody, Nudel antibody, 2600006O07Rik antibody, mNudel antibody, wu:fi23c04 antibody, wu:fi23e06 antibody, eopa antibody, mitap1 antibody, ndel1 antibody, ndel1-a antibody, ndel1-b antibody, nudel antibody, nudE neurodevelopment protein 1 like 1 antibody, nudE neurodevelopment protein 1-like 1 antibody, nudE neurodevelopment protein 1-like 1b antibody, nudE neurodevelopment protein 1 like 1 L homeolog antibody, NDEL1 antibody, Ndel1 antibody, ndel1b antibody, ndel1.L antibody
    背景
    Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.
    分子量
    38375
    UniProt
    Q9GZM8
    途径
    Regulation of Cell Size
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