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Nicastrin 抗体 (AA 650-750)

The 兔 单克隆 anti-Nicastrin antibody is suitable to detect Nicastrin in samples from 人. It has been validated for WB.
产品编号 ABIN6944227
发货至: 中国
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北京 101111
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Quick Overview for Nicastrin 抗体 (AA 650-750) (ABIN6944227)

抗原

See all Nicastrin (NCSTN) 抗体
Nicastrin (NCSTN)

适用

  • 88
  • 30
  • 26
  • 1
  • 1
  • 1
  • 1

宿主

  • 88
  • 2

克隆类型

  • 70
  • 20
单克隆

标记

  • 29
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Nicastrin antibody is un-conjugated

应用范围

  • 59
  • 17
  • 17
  • 17
  • 14
  • 14
  • 12
  • 10
  • 7
  • 6
  • 3
  • 2
Western Blotting (WB)

克隆位点

3F10
  • 抗原表位

    • 15
    • 13
    • 12
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 650-750

    原理

    Nicastrin (3F10) Monoclonal Antibody

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic peptide within Human Nicastrin aa 650-750 (C terminal).

    亚型

    IgG
  • 应用备注

    WB(1:300-5000)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Nicastrin (NCSTN)

    别名

    NCSTN

    背景

    Synonyms: Nicastrin, NCSTN, KIAA0253, ATAG1874

    Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

    基因ID

    23385

    UniProt

    Q92542

    途径

    Notch Signaling, Neurotrophin Signaling Pathway
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