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MUC1 抗体 (AA 1101-1255) (PE)

This anti-MUC1 antibody is a 兔 多克隆 antibody detecting MUC1 in WB 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6944165
发货至: 中国

Quick Overview for MUC1 抗体 (AA 1101-1255) (PE) (ABIN6944165)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MUC1 antibody is conjugated to PE

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

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    AA 1101-1255

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MUC1

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC1

    背景

    Synonyms: EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC, Mucin-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, Carcinoma-associated mucin, Episialin, Krebs von den Lungen-6, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin, MUC1

    Background: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

    基因ID

    4582

    UniProt

    P15941

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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