Growth Hormone Receptor 抗体 (AA 500-630)
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Quick Overview for Growth Hormone Receptor 抗体 (AA 500-630) (ABIN6943577)
抗原
See all Growth Hormone Receptor (GHR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 500-630
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原理
- Growth hormone receptor Recombinant Antibody
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交叉反应
- 人, 小鼠
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预测反应
- Rat
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic peptide within human Growth hormone receptor aa 500-630
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亚型
- IgG
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anti-Growth Hormone Receptor (GHR) (AA 101-200) antibody
GHR 适用: 人 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 353-588) antibodyGHR 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 19-118) antibodyGHR 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-Growth Hormone Receptor (GHR) antibodyGHR 适用: 人 ELISA, IHC, IF 宿主: 兔 Monoclonal 10C11 unconjugated Recombinant Antibody
anti-Growth Hormone Receptor (GHR) (AA 36-266) antibodyGHR 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 315-574) antibodyGHR 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 25-650) antibodyGHR 适用: 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 19-118) antibodyGHR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 36-85) antibodyGHR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 19-184) antibodyGHR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Growth Hormone Receptor (GHR)
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别名
- Growth hormone receptor
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背景
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Synonyms: Growth hormone receptor, Somatotropin receptor, Growth hormone-binding protein, Serum-binding protein, GH receptor, GH-binding protein, GHBP, GHR.
Background: GHR is a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. It is a receptor for pituitary gland growth hormone involved in regulating postnatal body growth. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene
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基因ID
- 2690
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UniProt
- P10912
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途径
- NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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