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Complement Factor H 抗体

CFH 适用: 人 WB, FACS, IF (cc) 宿主: 兔 Monoclonal 6F11 unconjugated
产品编号 ABIN6943395
发货至: 中国
  • 抗原 See all Complement Factor H (CFH) 抗体
    Complement Factor H (CFH)
    适用
    • 51
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    宿主
    • 43
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    克隆类型
    • 41
    • 22
    单克隆
    标记
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    This Complement Factor H antibody is un-conjugated
    应用范围
    • 47
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    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    Full length protein
    克隆位点
    6F11
    亚型
    IgG
    Top Product
    Discover our top product CFH Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Complement Factor H (CFH)
    别名
    Factor H (CFH 产品)
    别名
    AHUS1 antibody, AMBP1 antibody, ARMD4 antibody, ARMS1 antibody, CFHL3 antibody, FH antibody, FHL1 antibody, HF antibody, HF1 antibody, HF2 antibody, HUS antibody, Mud-1 antibody, NOM antibody, Sas-1 antibody, Sas1 antibody, Fh antibody, CFH antibody, im:7147412 antibody, si:ch211-207o17.2 antibody, fH antibody, armd4 antibody, arms1 antibody, cfh antibody, cfhl3 antibody, fhl1 antibody, hf1 antibody, hf2 antibody, hus antibody, complement factor H antibody, complement component factor h antibody, complement factor H-related protein 5 antibody, complement factor H L homeolog antibody, CFH antibody, Cfh antibody, cfh antibody, LOC100399888 antibody, LOC100733902 antibody, cfh.L antibody
    背景

    Synonyms: Complement factor H, H factor 1, CFH, HF, HF1, HF2

    Background: A glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where its binding to self-markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop. As a cofactor of the serine protease factor I, CFH also regulates proteolytic degradation of already-deposited C3b. In addition, mediates several cellular responses through interaction with specific receptors. For example, interacts with CR3/ITGAM receptor and thereby mediates the adhesion of human neutrophils to different pathogens. In turn, these pathogens are phagocytosed and destroyed.

    基因ID
    3075
    UniProt
    P08603
    途径
    Complement System, Cellular Response to Molecule of Bacterial Origin
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