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Recombinant Complement Factor H 抗体

This 兔 单克隆 antibody specifically detects Complement Factor H in WB. It exhibits reactivity toward 人.
产品编号 ABIN6943395
发货至: 中国
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Quick Overview for Recombinant Complement Factor H 抗体 (ABIN6943395)

抗原

See all Complement Factor H (CFH) 抗体
Complement Factor H (CFH)

抗体类型

Recombinant Antibody

适用

  • 91
  • 36
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宿主

  • 88
  • 27
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  • 1

克隆类型

  • 74
  • 45
  • 1
单克隆

标记

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  • 3
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  • 3
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  • 2
  • 2
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  • 2
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  • 1
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This Complement Factor H antibody is un-conjugated

应用范围

  • 77
  • 38
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  • 17
  • 7
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Western Blotting (WB)
  • 原理

    CFH Recombinant Antibody

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Full length protein

    亚型

    IgG
  • 应用备注

    WB(WB(1:500-2000))

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Complement Factor H (CFH)

    别名

    Factor H

    背景

    Synonyms: Complement factor H, H factor 1, CFH, HF, HF1, HF2

    Background: A glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where its binding to self-markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop. As a cofactor of the serine protease factor I, CFH also regulates proteolytic degradation of already-deposited C3b. In addition, mediates several cellular responses through interaction with specific receptors. For example, interacts with CR3/ITGAM receptor and thereby mediates the adhesion of human neutrophils to different pathogens. In turn, these pathogens are phagocytosed and destroyed.

    基因ID

    3075

    UniProt

    P08603

    途径

    Complement System, Cellular Response to Molecule of Bacterial Origin
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