ERK1/2 抗体
-
- 抗原 See all ERK1/2 (MAPK1/3) 抗体
- ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
-
适用
- 人, 小鼠, 大鼠, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 单克隆
-
标记
- This ERK1/2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠, 斑马鱼
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant Human ERK1 + ERK2 between 150 amino acids to C-terminus
- 克隆位点
- 3A12
- 亚型
- IgG
- Top Product
- Discover our top product MAPK1/3 Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
- 别名
- ERK1/2 (MAPK1/3 产品)
- 别名
- erk1/2 antibody, mitogen-activated protein kinase antibody, erk1/2 antibody
- 背景
-
Synonyms: ERK 1, ERK 2, ERK-2, ERK1, erk1/2, ERK2, ERT1, ERT2, Extracellular signalregulated kinase 1, Extracellular signal-regulated kinase 2, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAP kinase isoform p44, MAPK 1, MAPK 2, MAPK 3, Mapk1, MAPK2, MAPK3,Mitogen-activated protein kinase 1, Mitogenactivated protein kinase 2, MK01_HUMAN, p38, p40, p41, p42-MAPK, PRKM 2
Background: p44/42 MAP Kinase(Thr202), ERK (extracellular signal regulated kinase), also known as MAPK (mitogen activated protein kinase) has two closely related isoforms of 44 kDa and 42 kDa, respectively. These kinases belong to a family of serine/threonine kinases that are activated upon treatment of cells with a large variety of stimuli including mitogens, hormones, growth factors, cytokines, and bioactive peptides. Cell stimulation induces the activation of a signaling cascade, the downstream effects of which have been linked to the regulation of cell growth and differentiation as well as the cytoskeleton. ERK1 and ERK2 are phosphorylated within the activation loop on both a Threonine and a Tyrosine residue (within a Thr-Glu-Tyr motif) by MEKs (MAPK/ERK kinases), thereby greatly elevating the activity of ERK1&2.
- UniProt
- P27361, P28482
-