BMI1 抗体
Quick Overview for BMI1 抗体 (ABIN6942288)
抗原
See all BMI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- C terminal Human Bmi1
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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别名
- Bmi1
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背景
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Synonyms: Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1
Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
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UniProt
- P35226
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途径
- Cell Division Cycle, Autophagy
抗原
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