ATF4 抗体
Quick Overview for ATF4 抗体 (ABIN6942153)
抗原
See all ATF4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Human ATF4 between 20 to 200 amino acids
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亚型
- IgG
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anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) (AA 130-347) antibody
ATF4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) (AA 171-270) antibodyATF4 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B3 unconjugated
anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) (AA 212-351) antibodyATF4 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2A6F12 unconjugated
anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) (AA 251-351) antibodyATF4 适用: 人, 小鼠, 大鼠, 犬, 兔 WB, ELISA, IF (cc), IHC (p), IF (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) antibodyATF4 适用: 人 WB, IHC, ELISA, IP, IF, FACS 宿主: 兔 Monoclonal 9E1 unconjugated Recombinant Antibody
anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) (N-Term) antibodyATF4 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) (N-Term) antibodyATF4 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) (N-Term) antibodyATF4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) (AA 126-291) antibodyATF4 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) antibodyATF4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
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别名
- ATF4
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背景
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Synonyms: Cyclic AMP-dependent transcription factor ATF-4, Activating transcription factor 4, Cyclic AMP-responsive element-binding protein 2, DNA-binding protein TAXREB67, Tax-responsive enhancer element-binding protein 67, cAMP-dependent transcription factor ATF-4, CREB-2, cAMP-responsive element-binding protein 2, TaxREB67, ATF4
Background: Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
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基因ID
- 468
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UniProt
- P18848
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途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
抗原
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