CD51 抗体
Quick Overview for CD51 抗体 (ABIN6941316)
抗原
See all CD51 (ITGAV) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin Receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. Reacts with Integrin Alpha V Beta 3. 23C6 may be useful for bone resorption modulation, osteoclast identification, receptor purification, malignant melanoma identification and treatment.
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无交叉反应
- 牛, 猪, 兔
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纯化方法
- Purified by Protein A/G
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免疫原
- Osteoclasts from osteoclastomas
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亚型
- IgG1 kappa
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anti-Integrin alpha V (ITGAV) antibody
ITGAV 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Integrin alpha V (ITGAV) (C-Term) antibodyITGAV 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 560-744) antibodyITGAV 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 775-885) antibodyITGAV 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 51-150) antibodyITGAV 适用: 人, 小鼠 WB, FACS, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 71-322) antibodyITGAV 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) antibodyITGAV 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 1-1048) antibodyITGAV 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (AA 1-1048) antibodyITGAV 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-Integrin alpha V (ITGAV) (C-Term) antibodyITGAV 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: Squamous cells, A375M melanoma cells. A549 cells.
Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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别名
- ITGAV
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分子量
- 150-160kDa under non-reducing conditions. Under reducing conditions, it is cleaved into 2 bands of about 125-130kDa +20-25kDa.
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基因ID
- 3685
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UniProt
- P06756
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
抗原
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