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CD40 Ligand 抗体 (AA 108-261)

Name: CD40 Ligand 抗体 (AA 108-261)
Brand: antibodies-online
SKU: ABIN6941188
Availability: OutOfStock

This 小鼠单克隆 anti-CD40 Ligand antibody (Clone CD40LG-2761) specifically detects CD40 Ligand in FACS, IHC, ELISA, IF, Coat 和 StM. The antibody is reactive with 人 samples.

Formalin-fixed, paraffin-embedded human Spleen stained with CD40L-Monospecific Mouse Monoclonal Antibody (CD40LG/2761) (CD40 Ligand 抗体 (AA 108-261))

IHC

SDS-PAGE Analysis Purified CD40L Mouse Monoclonal Antibody (CD40LG/2761). (CD40 Ligand 抗体 (AA 108-261))

SDS

Analysis of Protein Array containing more than 19,000 full-length human proteins using CD40-Ligand Mouse Monoclonal Antibody (CD40LG/2761) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. (CD40 Ligand 抗体 (AA 108-261))

PAr

Flow Cytometric Analysis of Jurkat cells using CD40L-Monospecific Mouse Monoclonal Antibody (CD40LG/2761) followed by Goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red). (CD40 Ligand 抗体 (AA 108-261))

FACS

IHC

Formalin-fixed, paraffin-embedded human Tonsil stained with CD40L-Monospecific Mouse Monoclonal Antibody (CD40LG/2761). (CD40 Ligand 抗体 (AA 108-261))

IHC

Immunofluorescent staining of paraformaldehyde-fixed Jurkat cells using CD40L Mouse Monoclonal Antibody (CD40LG/2761) followed by goat anti-Mouse IgG conjugated to CF488 (green). (CD40 Ligand 抗体 (AA 108-261))

7 images

产品编号 ABIN6941188

发货至: 中国

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中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD40 Ligand 抗体 (AA 108-261) (ABIN6941188)

抗原

See all CD40 Ligand (CD40LG) 抗体

CD40 Ligand (CD40LG)

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This CD40 Ligand antibody is un-conjugated

应用范围

Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Coating (Coat), Staining Methods (StM)

克隆位点

CD40LG-2761

Discover our top product CD40LG Primary Antibody

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AA 108-261

纯化方法

Purified by Protein A/G

免疫原

Recombinant fragment (around aa 108-261) of human CD40LG protein (exact sequence is proprietary)

亚型

IgG2b kappa
anti-CD40 Ligand (CD40LG) (AA 1-261) antibody
CD40LG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 108-261) antibody
CD40LG 适用: 人 FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal CD40LG-2763 unconjugated

anti-CD40 Ligand (CD40LG) antibody (FITC)
CD40LG 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal MR-1 FITC

anti-CD40 Ligand (CD40LG) (AA 33-62) antibody
CD40LG 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 111-261) antibody
CD40LG 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) antibody (PE)
CD40LG 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal 24-31 PE

anti-CD40 Ligand (CD40LG) (AA 47-261) antibody
CD40LG 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5A3A9 unconjugated

anti-CD40 Ligand (CD40LG) (AA 47-261) antibody
CD40LG 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 8H10F5 unconjugated

anti-CD40 Ligand (CD40LG) (AA 47-65), (N-Term) antibody
CD40LG 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 33-62), (N-Term) antibody
CD40LG 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB19150 unconjugated

应用备注

Positive Control: Jurkat cells. Tonsil, Spleen or Thymus.
Known Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

限制

仅限研究用
浓度

200 μg/mL

缓冲液

10 mM PBS with 0.05 % BSA & 0.05 % azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-80 °C

储存方法

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

有效期

24 months
抗原

CD40 Ligand (CD40LG)

别名

CD40LG

背景

CD40LG expression is mainly confined to the CD4-positive-T-cell subset. Its expression is induced shortly after T-cell activation and represents an early activation marker of T lymphocytes. CD40 is constitutively expressed mainly on B cells, macrophages, and dendritic cells. The CD40-CD40L pathway has been shown to play multiple functional roles in the healthy immune system. It enhances the antigen-specific T-cell response through the activation of dendritic cells and the induction of interleukin-12 production. For example, engagement of CD40 on endothelial cells by activated T cells expressing CD40L leads to upregulation of adhesion molecules such as ICAM-1, VCAM-1, and E-selectin. Activation of APC by CD40-CD40L interaction induces the production of inflammatory cytokines, chemokines, NO, and metalloproteinases. Interaction of CD4-positiveCD40LG-positiveT cells with CD40 on B cells leads to B-cell differentiation, proliferation, immunoglobulin (Ig) isotype switching, and formation of memory B cells.

分子量

36kDa

基因ID

959

UniProt

P29965

途径

NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints