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CD3 epsilon 抗体 (AA 156-168)

This anti-CD3 epsilon antibody is a 兔 多克隆 antibody detecting CD3 epsilon in WB. Suitable for 人.
产品编号 ABIN6941037
发货至: 中国

Quick Overview for CD3 epsilon 抗体 (AA 156-168) (ABIN6941037)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

适用

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克隆类型

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多克隆

标记

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This CD3 epsilon antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 156-168

    特异性

    Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

    交叉反应 (详细)

    Predicted to react with Ape, Orangutan, Gibbon, Chimpanzee, Monkey, Elephant, Horse, Cow, Sheep, Pig, Dog, Cat, Rabbit, Rat, Mouse, Guinea Pig, Hamster, Opossum, Frog, Chicken.

    免疫原

    A synthetic peptide aa156-168 (ERPPPVPNPDYEP) from human CD3e

    亚型

    IgG
  • 应用备注

    Positive Control: Jurkat cells. Tonsil and lymph node.

    Known Application: Western Blot (1-2 μg/mL for 60 minutes at RT), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3E

    分子量

    20kDa

    基因ID

    916

    UniProt

    P07766

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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