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p63 抗体 (AA 3-106)

This 小鼠 单克隆 anti-p63 antibody (Clone TP63-1786) specifically detects p63 in WB, ELISA 和 Coat. The antibody is reactive with 人 samples.
产品编号 ABIN6940965
发货至: 中国
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Quick Overview for p63 抗体 (AA 3-106) (ABIN6940965)

抗原

See all p63 (TP63) 抗体
p63 (TP63) (Tumor Protein P63 (TP63))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This p63 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Coating (Coat)

克隆位点

TP63-1786
  • 抗原表位

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    AA 3-106

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment (around aa 3-106) of human p63 protein (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: HEK293 cells. Prostate Carcinoma or Lung or bladder squamous cell carcinoma.

    Known Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    p63 (TP63) (Tumor Protein P63 (TP63))

    别名

    TP63

    背景

    P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

    分子量

    63kDa

    基因ID

    8626

    UniProt

    Q9H3D4
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