Tyrosinase-Related Protein 1 抗体
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Quick Overview for Tyrosinase-Related Protein 1 抗体 (ABIN6940835)
抗原
See all Tyrosinase-Related Protein 1 (TYRP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Antibody
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特异性
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- SK-MEL-23 cells
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亚型
- IgG2a, kappa
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anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibody
TYRP1 适用: 人, 小鼠, 大鼠, 犬, 山羊, 马, 兔, 绵羊, Cow, 豚鼠, 斑马鱼 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 适用: 人 IHC, WB, ELISA 宿主: 兔 Monoclonal TYRP1-2340R unconjugated Recombinant Antibody
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal TYRP1-3280 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 198-227) antibodyTYRP1 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB19412 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibodyTYRP1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 396-445) antibodyTYRP1 适用: 人, 小鼠, 大鼠, 犬, 山羊, 马, 兔, 绵羊, 豚鼠, 斑马鱼, 小鸡, 猴, Bat IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 适用: 人, 小鼠 IHC 宿主: 兔 Monoclonal TYRP1-1564R unconjugated Recombinant Antibody
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应用备注
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Positive Control: SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Melanoma.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen only) (0.5-1 μg/mL for 30 minutes at RT)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Tyrosinase-Related Protein 1 (TYRP1)
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别名
- TYRP1
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背景
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5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP
SK-MEL-19, SK-MEL-23, SK-MEL-30, SK-MEL-37 cells. Melanoma.
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分子量
- 75kDa
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基因ID
- 7306, 270279
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UniProt
- P17643
抗原
-
