BMI1 抗体 (AA 142-326)
Quick Overview for BMI1 抗体 (AA 142-326) (ABIN6940580)
抗原
See all BMI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 142-326
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant fragment of human BMI1 protein (around aa 142-326) (exact sequence is proprietary)
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亚型
- IgG1 kappa
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应用备注
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Positive Control: 293T, NIH3T3, HeLa or Jurkat cells. Colon Carcinoma.
Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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别名
- BMI1
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背景
- The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies.
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分子量
- 41kDa
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基因ID
- 648
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UniProt
- P35226
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途径
- Cell Division Cycle, Autophagy
抗原
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