电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

JUP 抗体

This anti-JUP antibody is a 小鼠 单克隆 antibody detecting JUP in WB, IF 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN6939838
发货至: 中国

Quick Overview for JUP 抗体 (ABIN6939838)

抗原

See all JUP 抗体
JUP (Junction Plakoglobin (JUP))

适用

  • 172
  • 72
  • 64
  • 35
  • 27
  • 25
  • 24
  • 4
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 102
  • 70
  • 2
  • 1
小鼠

克隆类型

  • 92
  • 83
单克隆

标记

  • 75
  • 12
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This JUP antibody is un-conjugated

应用范围

  • 113
  • 70
  • 50
  • 41
  • 33
  • 26
  • 26
  • 24
  • 18
  • 16
  • 10
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

1-10E05
  • 特异性

    It recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (, , and ) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. T-catenin binds to E-catenin as well as to -catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for -T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant full length human plakoglobin, fused to maltose binding protein

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: HeLa, SK-BR3, HT20, A549, 293 or A431 cells. Skin.

    Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Western Blot (0.5-2 μg/mL),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    JUP (Junction Plakoglobin (JUP))

    别名

    JUP

    分子量

    80-87kDa

    基因ID

    3728

    UniProt

    P14923

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location
You are here:
Chat with us!