JUP 抗体
Quick Overview for JUP 抗体 (ABIN6939838)
抗原
See all JUP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- It recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (, , and ) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. T-catenin binds to E-catenin as well as to -catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for -T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant full length human plakoglobin, fused to maltose binding protein
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亚型
- IgG1 kappa
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anti-Junction Plakoglobin (JUP) antibody
JUP 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Junction Plakoglobin (JUP) (AA 1-745) antibodyJUP 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Junction Plakoglobin (JUP) (C-Term) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Junction Plakoglobin (JUP) (C-Term) antibodyVerified JUP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) (AA 556-745) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人 WB, IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal CTNG-1664 unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, Cat WB, IF, FACS 宿主: 小鼠 Monoclonal 15F11 unconjugated
anti-Junction Plakoglobin (JUP) (AA 1-300) antibodyJUP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: HeLa, SK-BR3, HT20, A549, 293 or A431 cells. Skin.
Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Western Blot (0.5-2 μg/mL),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- JUP (Junction Plakoglobin (JUP))
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别名
- JUP
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分子量
- 80-87kDa
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基因ID
- 3728
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UniProt
- P14923
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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