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HLA-DRA 抗体

The 小鼠 单克隆 anti-HLA-DRA antibody is suitable to detect HLA-DRA in samples from 人, Cow 和 Cat. It has been validated for FACS 和 IF.
产品编号 ABIN6939637
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HLA-DRA 抗体 (ABIN6939637)

抗原

See all HLA-DRA 抗体
HLA-DRA (HLA Class II DR alpha (HLA-DRA))

适用

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人, Cow, Cat

宿主

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小鼠

克隆类型

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单克隆

标记

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This HLA-DRA antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

169-1B5-2
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Human peripheral blood leukocytes

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Ramos, Daudi or HuT78 cells. Tonsil or lymph node.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    HLA-DRA (HLA Class II DR alpha (HLA-DRA))

    别名

    HLA-DRA

    背景

    This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

    分子量

    36kDa (α, chain) and 27kDa (β, chain)

    基因ID

    3122

    UniProt

    P01903

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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