Recombinant AMACR 抗体 (AA 297-394)
Quick Overview for Recombinant AMACR 抗体 (AA 297-394) (ABIN6939429)
抗原
See all AMACR 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 297-394
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特异性
- This antibody recognizes a protein of 42 kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant human AMACR protein fragment (around aa 297-394) (exact sequence is proprietary)
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亚型
- IgG1 kappa
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anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibody
AMACR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal AMACR-1864 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal AMACR-1723 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 1-198) antibodyAMACR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人, 小鼠 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 2A10F3 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 323-351) antibodyAMACR 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 312-326) antibodyVerified AMACR 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibodyAMACR 适用: 人 IHC, StM 宿主: 兔 Monoclonal AMACR-2748R unconjugated Recombinant Antibody
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人 IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 323-351), (C-Term) antibodyAMACR 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18736 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1F1 unconjugated
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应用备注
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Positive Control: HEK cells. Prostate Adenocarcinoma.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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别名
- AMACR
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分子量
- 42kDa
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基因ID
- 23600
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UniProt
- Q9UHK6
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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