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Fibronectin 1 抗体

This 小鼠 单克隆 anti-Fibronectin 1 antibody (Clone TV-1) specifically detects Fibronectin 1 in IHC, IF, FACS 和 StM. The antibody is reactive with 人, 小鼠, 大鼠 和 Pig samples.
产品编号 ABIN6939411
发货至: 中国
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Quick Overview for Fibronectin 1 抗体 (ABIN6939411)

抗原

See all Fibronectin 1 (FN1) 抗体
Fibronectin 1 (FN1)

适用

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人, 小鼠, 大鼠, Pig

宿主

  • 81
  • 33
  • 1
  • 1
小鼠

克隆类型

  • 75
  • 40
单克隆

标记

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This Fibronectin 1 antibody is un-conjugated

应用范围

  • 74
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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)

克隆位点

TV-1
  • 特异性

    Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.

    纯化方法

    Purified by Protein A/G

    免疫原

    T-cell lymphoma biopsy

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: SW156 cells. Kidney.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Fibronectin 1 (FN1)

    别名

    FN1

    分子量

    220kDa (monomer), 440kDa (dimer)

    基因ID

    2335

    UniProt

    P02751

    途径

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy
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