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Recombinant YBX1 抗体

This anti-YBX1 antibody is a 小鼠 单克隆 antibody detecting YBX1 in IHC (f). Suitable for 人.
产品编号 ABIN6938791
发货至: 中国

Quick Overview for Recombinant YBX1 抗体 (ABIN6938791)

抗原

See all YBX1 抗体
YBX1 (Y Box Binding Protein 1 (YBX1))

抗体类型

Recombinant Antibody

适用

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宿主

  • 92
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小鼠

克隆类型

  • 83
  • 40
单克隆

标记

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This YBX1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

RYBX1-2430
  • 特异性

    The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant human full-length YBX1 protein

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    YBX1 (Y Box Binding Protein 1 (YBX1))

    别名

    YBX1

    背景

    BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1,YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker)
    Cellular localisation: Cytoplasmic and Nuclear

    分子量

    36kDa

    基因ID

    4904, 473583

    UniProt

    P67809

    途径

    Regulation of Muscle Cell Differentiation
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