Tyrosinase-Related Protein 1 抗体
Our Local Distributor
北京 101111
Quick Overview for Tyrosinase-Related Protein 1 抗体 (ABIN6938714)
抗原
See all Tyrosinase-Related Protein 1 (TYRP1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
-
交叉反应 （详细）
- Human. Mouse.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant human TYRP1 protein
-
亚型
- IgG
-
-
anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibody
TYRP1 适用: 人, 小鼠, 大鼠, 犬, 山羊, 马, 兔, 绵羊, Cow, 豚鼠, 斑马鱼 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 适用: 人 IHC, ELISA, StM, Coat 宿主: 兔 Monoclonal TYRP1-2340R unconjugated Recombinant Antibody
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal TYRP1-3280 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 198-227) antibodyTYRP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19412 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 396-445) antibodyTYRP1 适用: 人, 小鼠, 大鼠, 犬, 山羊, 马, 兔, 绵羊, 豚鼠, 斑马鱼, 猴, 小鸡, Bat IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 适用: 人, 小鼠 IHC, StM 宿主: 兔 Monoclonal TYRP1-1564R unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 适用: 人, 小鼠 IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibodyTYRP1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Known_Application: Immunohistochemistry (Formalin-fixed) (5-10 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Melanoma.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- Tyrosinase-Related Protein 1 (TYRP1)
-
别名
- TYRP1
-
背景
-
5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP,Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)
Cellular localisation: Cytoplasmic -
分子量
- 75kDa
-
基因ID
- 7306, 270279
-
UniProt
- P17643
抗原
-
