Tyrosinase-Related Protein 1 抗体 (AA 257-377)
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- 抗原 See all Tyrosinase-Related Protein 1 (TYRP1) 抗体
- Tyrosinase-Related Protein 1 (TYRP1)
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抗原表位
- AA 257-377
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Tyrosinase-Related Protein 1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)
- 特异性
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary)
- 克隆位点
- TYRP1-3280
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product TYRP1 Primary Antibody
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anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibody
TYRP1 适用: 人, 小鼠, 大鼠, 犬, 山羊, 马, 兔, 绵羊, Cow, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 适用: 人 IHC, ELISA, StM, Coat 宿主: 兔 Monoclonal TYRP1-2340R unconjugated Recombinant Antibody
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal TYRP1-3280 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 198-227) antibodyTYRP1 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB19412 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 适用: 人, 小鼠 IHC, StM 宿主: 兔 Monoclonal TYRP1-1564R unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 适用: 人, 小鼠 IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 396-445) antibodyTYRP1 适用: 人, 小鼠, 大鼠, 犬, 山羊, 马, 兔, 绵羊, 豚鼠, 斑马鱼, 猴, 小鸡, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibodyTYRP1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Human skin or melanoma tissues (IHC).
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- Tyrosinase-Related Protein 1 (TYRP1)
- 别名
- TYRP1 (TYRP1 产品)
- 背景
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5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75,Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)
Cellular localisation: Cytoplasmic - 分子量
- 75kDa
- 基因ID
- 7306, 270279
- UniProt
- P17643
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