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Tyrosinase-Related Protein 1 抗体

TYRP1 适用: 人 IF, FACS, WB, IHC (fro) 宿主: 小鼠 Monoclonal TA99-TYRP1-807 unconjugated
产品编号 ABIN6938702
发货至: 中国
  • 抗原 See all Tyrosinase-Related Protein 1 (TYRP1) 抗体
    Tyrosinase-Related Protein 1 (TYRP1)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Tyrosinase-Related Protein 1 antibody is un-conjugated
    应用范围
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    Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
    交叉反应 (详细)
    Human. Mouse.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    SK-MEL-23 cells (TA99), Recombinant full-length human TYRP1 protein (TYRP1/807)
    克隆位点
    TA99-TYRP1-807
    亚型
    IgG2a kappa
    Top Product
    Discover our top product TYRP1 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Frozen only) (1-2 μg/mL for 30 minutes at RT)Optimal dilution for a specific application should be determined.

    Positive_Control: SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Melanoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Tyrosinase-Related Protein 1 (TYRP1)
    别名
    TYRP1 (TYRP1 产品)
    别名
    CAS2 antibody, CATB antibody, GP75 antibody, OCA3 antibody, TRP antibody, TRP1 antibody, TYRP antibody, b-PROTEIN antibody, LOC397853 antibody, Trypsin antibody, hm:zeh0659 antibody, tyrp1 antibody, zgc:100893 antibody, B antibody, TYRP1 antibody, tyrp-1 antibody, TRP-1 antibody, Tyrp antibody, b antibody, brown antibody, isa antibody, tyrosinase related protein 1 antibody, protease, serine 1 L homeolog antibody, tyrosinase-related protein 1b antibody, tyrosinase-related protein 1 antibody, tyrosinase-related protein 1 L homeolog antibody, tyrosinase-related protein 1a antibody, TYRP1 antibody, prss1.L antibody, tyrp1b antibody, Tyrp1 antibody, tyrp1.L antibody, tyrp1 antibody, LOC100136490 antibody, tyrp-1 antibody, tyrp1a antibody
    背景
    5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP,Tyrosinase-Related Protein-1 (TRP-1) (Melanoma Marker)
    Cellular localisation: Cytoplasmic
    分子量
    75kDa
    基因ID
    7306, 270279
    UniProt
    P17643
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