STAT2 抗体
Quick Overview for STAT2 抗体 (ABIN6938459)
抗原
See all STAT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
-
交叉反应 (详细)
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant full-length human STAT2 protein
-
亚型
- IgG1 kappa
-
-
-
-
应用备注
-
Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Ramos and Jurkat cell lysates. HeLa cell extract. Human lung carcinoma tissue.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
-
别名
- STAT2
-
背景
-
Homo sapiens interferon alpha induced transcriptional activator, interferon alpha induced transcriptional activator (ISGF3), P113, signal transducer and activator of transcription 2 113kD (STAT113), Signal transducer and activator of transcription 2 (STAT2),STAT2
Cellular localisation: Cell surface. -
分子量
- 113kDa
-
基因ID
- 6773, 530595
-
UniProt
- P52630
-
途径
- JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
抗原
-