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Melanoma gp100 抗体

PMEL 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal NKI-beteb unconjugated
产品编号 ABIN6938384
发货至: 中国
  • 抗原 See all Melanoma gp100 (PMEL) 抗体
    Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Melanoma gp100 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
    无交叉反应
    大鼠
    交叉反应 (详细)
    Human. Horse. Does not react with Rat.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Membranes from a human melanoma metastasis
    克隆位点
    NKI-beteb
    亚型
    IgG2b kappa
    Top Product
    Discover our top product PMEL Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: SK-MEL-28 cells. Melanoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
    别名
    SILV (PMEL 产品)
    别名
    D12S53E antibody, ME20 antibody, ME20-M antibody, ME20M antibody, P1 antibody, P100 antibody, PMEL17 antibody, SI antibody, SIL antibody, SILV antibody, gp100 antibody, D10H12S53E antibody, D12S53Eh antibody, Pmel17 antibody, Si antibody, Silv antibody, gp87 antibody, RPE1 antibody, MMP115 antibody, silverb antibody, silver antibody, cb397 antibody, fdv antibody, pmel17 antibody, sb:cb397 antibody, silva antibody, wu:fc11g11 antibody, wu:fj24g11 antibody, zgc:136622 antibody, premelanosome protein antibody, premelanosome protein b antibody, premelanosome protein a antibody, PMEL antibody, Pmel antibody, pmelb antibody, pmela antibody
    背景
    95 kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog,gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)
    Cellular localisation: Cytoplasmic
    分子量
    90-100kDa
    基因ID
    6490, 95972
    UniProt
    P40967
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