Recombinant ODC1 抗体
Quick Overview for Recombinant ODC1 抗体 (ABIN6938107)
抗原
See all ODC1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
-
交叉反应 (详细)
- Human. Mouse. Rat.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant full-length human ODC-1 protein
-
亚型
- IgG
-
-
-
-
应用备注
-
Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: PC3 cells. Placenta, Prostate or Testicular carcinoma.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- ODC1 (Ornithine Decarboxylase 1 (ODC1))
-
别名
- ODC1
-
背景
-
Ornithine decarboxylase structural 1, RNODC,Ornithine Decarboxylase-1 (ODC-1)
Cellular localisation: Cytoplasmic -
分子量
- 53kDa
-
基因ID
- 4953, 467701
-
UniProt
- P11926
抗原
-