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ODC1 抗体

This anti-ODC1 antibody is a 小鼠 单克隆 antibody detecting ODC1 in WB, IF, FACS 和 IHC (f). Suitable for 人.
产品编号 ABIN6938104
发货至: 中国

Quick Overview for ODC1 抗体 (ABIN6938104)

抗原

See all ODC1 抗体
ODC1 (Ornithine Decarboxylase 1 (ODC1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ODC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

ODC1-486
  • 特异性

    Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

    交叉反应 (详细)

    Human. Mouse. Rat.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant human ODC-1 protein

    亚型

    IgG2a kappa
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: PC3 cells. Placenta, Prostate or Testicular carcinoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    ODC1 (Ornithine Decarboxylase 1 (ODC1))

    别名

    ODC1

    背景

    Ornithine decarboxylase structural 1, RNODC,Ornithine Decarboxylase-1 (ODC-1)
    Cellular localisation: Cytoplasmic

    分子量

    53kDa

    基因ID

    4953, 467701

    UniProt

    P11926
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