Nkx2-2 抗体
Quick Overview for Nkx2-2 抗体 (ABIN6938068)
抗原
See all Nkx2-2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human NKX2.2 protein fragment
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亚型
- IgG
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anti-NK2 Homeobox 2 (Nkx2-2) (AA 1-119) antibody
Nkx2-2 适用: 人 IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal NX2-1524 unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) (AA 1-119) antibodyNkx2-2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal NX2-1523 unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) antibodyNkx2-2 适用: 人, 小鼠, 大鼠, 小鸡 IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal NX2-294 unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) antibodyNkx2-2 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) (N-Term) antibodyNkx2-2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) antibodyNkx2-2 适用: 人, 小鼠, 大鼠, 小鸡 IHC, StM 宿主: 小鼠 Monoclonal rNX2-294 unconjugated Recombinant Antibody
anti-NK2 Homeobox 2 (Nkx2-2) (AA 1-119) antibodyNkx2-2 适用: 人 IHC, StM 宿主: 兔 Monoclonal NX2-2198R unconjugated
anti-NK2 Homeobox 2 (Nkx2-2) antibodyNkx2-2 适用: 人 IHC, StM 宿主: 兔 Monoclonal NX2-1422R unconjugated Recombinant Antibody
anti-NK2 Homeobox 2 (Nkx2-2) (AA 1-119) antibodyNkx2-2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rNX2-1523 unconjugated Recombinant Antibody
anti-NK2 Homeobox 2 (Nkx2-2) (N-Term) antibodyNkx2-2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
Positive_Control: Pancreas or Ewing's sarcoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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别名
- NKX2-2
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背景
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Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman,NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker)
Cellular localisation: Nuclear -
分子量
- 40-50kDa
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基因ID
- 4821, 516922
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UniProt
- O95096
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途径
- Dopaminergic Neurogenesis
抗原
-
