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MUC5AC 抗体

This anti-MUC5AC antibody is a 小鼠 单克隆 antibody detecting MUC5AC in IHC, IF, FACS 和 IHC (f). Suitable for 人.
产品编号 ABIN6937958
发货至: 中国

Quick Overview for MUC5AC 抗体 (ABIN6937958)

抗原

See all MUC5AC 抗体
MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MUC5AC antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

SPM297
  • 特异性

    This MAb recognizes the peptide core of gastric mucin M1 (1,000 kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.

    无交叉反应

    交叉反应 (详细)

    Human. Monkey. Rabbit. Cat. Mouse. Rat. Pig. Hedgehog. Chicken. Does not react with Cow.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Human colon or stomach (IHC).

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

    别名

    MUC5AC

    背景

    Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM),MUC5AC (Mucin 5AC / Gastric Mucin)
    Cellular localisation: Cytoplasmic

    分子量

    >1,000kDa

    基因ID

    4586, 534332

    UniProt

    P98088
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