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MUC5AC 抗体

MUC5AC 适用: 人 IHC, IHC (f) 宿主: 小鼠 Monoclonal 45M1 unconjugated
产品编号 ABIN6937957
发货至: 中国
  • 抗原 See all MUC5AC 抗体
    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MUC5AC antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
    无交叉反应
    交叉反应 (详细)
    Human. Monkey. Rabbit. Cat. Mouse. Rat. Pig. Hedgehog. Chicken. Does not react with Cow.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
    克隆位点
    45M1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MUC5AC Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Human colon or stomach (IHC).

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
    别名
    MUC5AC (MUC5AC 产品)
    别名
    MUC5 antibody, TBM antibody, leB antibody, 2210005L13Rik antibody, MGM antibody, mucin 5AC, oligomeric mucus/gel-forming antibody, putative gastric mucin antibody, mucin 5, subtypes A and C, tracheobronchial/gastric antibody, mucin 2, oligomeric mucus/gel-forming antibody, MUC5AC antibody, Smp_144070 antibody, Muc5ac antibody, MUC2 antibody
    背景
    Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM),MUC5AC (Mucin 5AC / Gastric Mucin)
    Cellular localisation: Cytoplasmic
    分子量
    >1,000kDa
    基因ID
    4586, 534332
    UniProt
    P98088
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