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MUC1 抗体

This anti-MUC1 antibody is a 小鼠 单克隆 antibody detecting MUC1 in IHC (f). Suitable for 人.
产品编号 ABIN6937928
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for MUC1 抗体 (ABIN6937928)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

MUC1-520
  • 特异性

    In Western blotting, it recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of EMA. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Human milk-fat globule membranes (HMFGM)

    亚型

    IgG2a kappa
  • 应用备注

    Known_Application: Immunohistology (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC1

    背景

    Breast carcinoma-associated antigen DF3, CA15-3, Carcinoma-associated mucin Episialin, Epithelial Membrane Antigen, H23AG, KL-6, MAM6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, Mucin 1 cell surface associated, Mucin-1 subunit beta, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor-associated epithelial membrane antigen, Tumor-associated mucin,MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker)
    Cellular localisation: Cytoplasmic & Cell Surface

    分子量

    265-400kDa

    基因ID

    4582, 89603

    UniProt

    P15941

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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