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MUC1 抗体

MUC1 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal VU-2G7 unconjugated
产品编号 ABIN6937920
发货至: 中国
  • 抗原 See all MUC1 抗体
    MUC1 (Mucin 1 (MUC1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MUC1 antibody is un-conjugated
    应用范围
    • 137
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    ELISA, Coating (Coat)
    特异性
    MAb VU-2G7 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of VU-2G7 has not been established with 'epitope fingerprinting'. The'extra cellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Synthetic glycosylated MUC1 60mer tandem repeat NH2-(HGVTSAPDT(GalNAc)RPAPGSTAPPAHG)3- COOH, conjugated to bovine serum albumin
    克隆位点
    VU-2G7
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MUC1 Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA) Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    MUC1 (Mucin 1 (MUC1))
    别名
    MUC1 (MUC1 产品)
    别名
    CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
    背景
    Breast carcinoma-associated antigen DF3, CA15-3, Carcinoma-associated mucin Episialin, Epithelial Membrane Antigen, H23AG, KL-6, MAM6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, Mucin 1 cell surface associated, Mucin-1 subunit beta, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor-associated epithelial membrane antigen,MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker)
    Cellular localisation: Cytoplasmic and Cell Surface
    分子量
    265-400kDa
    基因ID
    4582, 89603
    UniProt
    P15941
    途径
    Negative Regulation of intrinsic apoptotic Signaling
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