LSP1 抗体 (AA 174-278)
Quick Overview for LSP1 抗体 (AA 174-278) (ABIN6937790)
抗原
See all LSP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 174-278
-
特异性
- LSP1 is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein. However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes, stromal cells and fibroblasts), suggesting pp52 has a divergent role in signal transduction. The pp52 (LSP1) locus maps to human chromosome 11p15.5, which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia. The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA, tandem pairs of Ets and SP1 motifs, and a single C/EBP motif. LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions, including cell motility and chemotaxis.
-
交叉反应 （详细）
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant fragment of human LSP1 protein (around aa174-278) (exact sequence is proprietary)
-
亚型
- IgG1 kappa
-
-
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 174-278) antibody
LSP1 适用: 人 IHC, IHC (p), StM 宿主: 小鼠 Monoclonal LSP1-3025 unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) antibodyLSP1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 241-339) antibodyLSP1 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 127-331) antibodyLSP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (C-Term) antibodyVerified LSP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 240-338) antibodyLSP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 1-339) antibodyLSP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 108-134) antibodyLSP1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20589 unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (pSer204) antibodyLSP1 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Specific Protein 1 (LSP1) (AA 1-339) antibodyLSP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Known_Application: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Human tonsil, colon, spleen or Hodgkin's lymphoma (IHC-P).
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- LSP1 (Lymphocyte-Specific Protein 1 (LSP1))
-
别名
- LSP1
-
背景
-
WP34, pp52, lymphocyte specific protein 1, leukocyte specific protein 1,Lymphocyte Specific Protein 1 (LSP1) / pp52
Cellular localisation: Membrane. -
分子量
- 52kDa
-
基因ID
- 4046, 56729
-
UniProt
- P33241
抗原
-
