VEGFR2/CD309 抗体
Quick Overview for VEGFR2/CD309 抗体 (ABIN6937619)
抗原
See all VEGFR2/CD309 (VEGFR2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- CD309, also known as VEGFR2, KDR3, and Flk-1 (Mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGFR2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human VEGF-R2 protein
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亚型
- IgG1 kappa
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anti-VEGF Receptor 2 (VEGFR2) (AA 20-200) antibody
VEGFR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-VEGF Receptor 2 (VEGFR2) (pTyr951) antibodyVEGFR2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-VEGF Receptor 2 (VEGFR2) (AA 20-242) antibodyVEGFR2 适用: 人 WB, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-VEGF Receptor 2 (VEGFR2) (AA 1326-1356) antibodyVEGFR2 适用: 人 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-VEGF Receptor 2 (VEGFR2) (AA 101-200) antibodyVEGFR2 适用: 人, 小鼠, 大鼠, 兔 ELISA, FACS, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-VEGF Receptor 2 (VEGFR2) (pTyr1214) antibodyVEGFR2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-VEGF Receptor 2 (VEGFR2) (AA 20-764) antibodyVEGFR2 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4B4 unconjugated
anti-VEGF Receptor 2 (VEGFR2) (AA 1225-1356) antibodyVEGFR2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A9A3 unconjugated
anti-VEGF Receptor 2 (VEGFR2) (AA 454-469), (Middle Region) antibodyVEGFR2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-VEGF Receptor 2 (VEGFR2) (AA 1326-1356), (C-Term) antibodyVEGFR2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB01536 unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Functional Studies (Order Ab without BSA & Azide), Optimal dilution for a specific application should be determined.
Positive_Control: HUVEC cells. Human lymph nodes and tonsils.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
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别名
- KDR
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背景
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CD309, Fetal liver kinase 1 (FLK-1), KDR, Kinase insert domain receptor (a type III receptor tyrosine kinase), KRD1, Ly73, Protein tyrosine kinase receptor FLK1, Protein-tyrosine kinase receptor flk-1, Vascular endothelial growth factor receptor 2,VEGFR2 / CD309 / Flk-1 / KDR3 (Hemangioblast Marker)
Cellular localisation: Cell Surface -
分子量
- 150-230kDa
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基因ID
- 3791, 479756
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UniProt
- P35968
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途径
- RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
抗原
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