电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

JUP 抗体

JUP 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 1-10E05 unconjugated
产品编号 ABIN6937612
发货至: 中国
  • 抗原 See all JUP 抗体
    JUP (Junction Plakoglobin (JUP))
    适用
    • 149
    • 60
    • 52
    • 23
    • 18
    • 14
    • 13
    • 4
    • 2
    • 1
    • 1
    • 1
    宿主
    • 93
    • 56
    • 2
    • 1
    小鼠
    克隆类型
    • 85
    • 67
    单克隆
    标记
    • 68
    • 11
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This JUP antibody is un-conjugated
    应用范围
    • 112
    • 54
    • 36
    • 35
    • 33
    • 27
    • 26
    • 24
    • 18
    • 10
    • 10
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    特异性
    It recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (, , and ) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. T-catenin binds to E-catenin as well as to -catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for -T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.
    交叉反应 (详细)
    Human. Mouse.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full length human plakoglobin, fused to maltose binding protein
    克隆位点
    1-10E05
    亚型
    IgG1 kappa
    Top Product
    Discover our top product JUP Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, SK-BR3, HT20, A549, 293 or A431 cells. Skin.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    JUP (Junction Plakoglobin (JUP))
    别名
    JUP (JUP 产品)
    别名
    ARVD12 antibody, CTNNG antibody, DP3 antibody, DPIII antibody, PDGB antibody, PKGB antibody, arvd12 antibody, ctnng antibody, dp3 antibody, dpiii antibody, pdgb antibody, pkgb antibody, plak antibody, D930025P04Rik antibody, PG antibody, cb80 antibody, danPG antibody, fb11b06 antibody, jup antibody, wu:fb11b06 antibody, junction plakoglobin antibody, junction plakoglobin L homeolog antibody, Junction plakoglobin antibody, junction plakoglobin a antibody, junction plakoglobin S homeolog antibody, JUP antibody, Jup antibody, jup antibody, jup.L antibody, Tsp_06656 antibody, plak antibody, jupa antibody, jup.S antibody
    背景
    ARVD12, Catenin (cadherin-associated protein), gamma 80 kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB,Catenin, gamma (Cardiomyocyte Marker)
    Cellular localisation: Cell Surface and Cytoplasmic
    分子量
    80-87kDa
    基因ID
    3728, 514174
    UniProt
    P14923
    途径
    Cell-Cell Junction Organization, Maintenance of Protein Location
You are here:
客服