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Integrin beta 2 抗体

This anti-Integrin beta 2 antibody is a 小鼠 单克隆 antibody detecting Integrin beta 2 in FACS, IF 和 Func. Suitable for 人.
产品编号 ABIN6937597
发货至: 中国

Quick Overview for Integrin beta 2 抗体 (ABIN6937597)

抗原

See all Integrin beta 2 (ITGB2) 抗体
Integrin beta 2 (ITGB2)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Integrin beta 2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

克隆位点

68-5A5
  • 特异性

    Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Stimulated human leukocytes

    亚型

    IgG2a kappa
  • 应用备注

    Known_Application: Functional Studies (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: Lymphocytes, granulocytes and macrophages in tonsil or lymph node.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Integrin beta 2 (ITGB2)

    别名

    ITGB2

    背景

    Beta 2 (antigen CD18 (p95), CD18, Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement component 3 receptor 3 and 4 subunit, Complement receptor C3 beta subunit, Integrin beta-2 (ITGB2), LAD, LCAMB, Leukocyte Cell Adhesion Molecule CD18, Lymphocyte function associated antigen 1 (LFA1), MAC1, Macrophage antigen 1 (mac1) beta,CD18 / Integrin beta-2 (ITGB2)
    Cellular localisation: Cell Surface

    分子量

    95kDa

    基因ID

    3689, 375957

    UniProt

    P05107

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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