HLA-DRA 抗体
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北京 101111
Quick Overview for HLA-DRA 抗体 (ABIN6937412)
抗原
See all HLA-DRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- MAb IPO-10 defines the antigen, which appears on B cell progenitors following HLA-DR and preceding CD10, CD19, CD22, CD37 and cym. It is expressed on resting B cells and than reappears and persists in cytoplasm and on cell surface until cytoplasmic Ig appears. It is a useful antibody for diagnostics of neoplasms of B cell origins. It reacts with human B cell lines Daudi, Raji, Namalva, EB-3, RPMI-8226 (50% of cells). The MAb does not label T cell lines, blood granulocytes, thymocytes or bone marrow stromal fibroblasts. No significant changes are detected after PHA or ConA stimulation while LPS and PWM stimulated cultures after 18-48h show decreased number of antigen-positive cells but in final terms of cultivation antigen is expressed again. This MAb labels B cell leukemias and some lymphomas. Hairy cell leukemia strongly reacts and 70% of B cell CLL and some B-NHL were also positive. IPO-10 reacts with AMML cells and in a majority of Hodgkin's disease cases a significant percentage of affected lymph node cells were detected. '
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交叉反应 （详细）
- Human. Monkey.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Spleen cells of a patient with hairy cell leukemia (Daudi cells)
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亚型
- IgG3 kappa
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anti-HLA Class II DR alpha (HLA-DRA) (AA 26-254) antibody
HLA-DRA 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 1C11A5 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 26-216) antibodyHLA-DRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 27-216) antibodyHLA-DRA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人 IHC 宿主: 兔 Monoclonal 470R unconjugated Recombinant Antibody
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 1-254) antibodyHLA-DRA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal 19-26-1-same as MB-26-1 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 26-221) antibody (APC)HLA-DRA 适用: 兔 WB, IHC 宿主: 豚鼠 Polyclonal APC
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Ramos, Daudi or HuT78 cells. Tonsil or lymph node.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- HLA-DRA (HLA Class II DR alpha (HLA-DRA))
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别名
- HLA-DRA
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背景
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DR alpha chain, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen DR alpha chain, HLA DRA, HLA DRA1, HLA-DRA, HLADRA1, Major histocompatibility complex class II DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA,HLA-DRA (MHC II)
Cellular localisation: Cell surface -
分子量
- ~36kDa
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基因ID
- 3122, 520048
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UniProt
- P01903
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途径
- TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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