GJB1 抗体
Quick Overview for GJB1 抗体 (ABIN6937323)
抗原
See all GJB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called 'connexons' that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane therefore, one connexin usually cannot fully substitute for another.
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交叉反应 (详细)
- Human. Mouse. Rat.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human GJB1 protein
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亚型
- IgG
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 cells. Liver, Kidney, Stomach or Tonsil.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
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别名
- GJB1
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背景
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Charcot Marie Tooth neuropathy X linked, CMTX, CMTX1, Connexin-32, Cx32, GAP junction 28 kDa liver protein, Gap junction beta-1 protein, Gap junction protein beta 1 32kD, GJB1,Connexin 32 (Gap Junction Protein)
Cellular localisation: Cytoplasmic and Cell Surface -
分子量
- 27-32kDa
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基因ID
- 2705, 333303
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UniProt
- P08034
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途径
- Cell-Cell Junction Organization
抗原
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