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GJB1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects GJB1 in WB 和 IHC. It exhibits reactivity toward 人, 大鼠, 小鼠, 犬, Cow, 马, 兔 和 豚鼠.It has been mentioned in 1 publication
产品编号 ABIN2774855
发货至: 中国
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Quick Overview for GJB1 抗体 (C-Term) (ABIN2774855)

抗原

See all GJB1 抗体
GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

适用

  • 106
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人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 豚鼠

宿主

  • 99
  • 25
  • 12
兔

克隆类型

  • 88
  • 48
多克隆

标记

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  • 1
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  • 1
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This GJB1 antibody is un-conjugated

应用范围

  • 71
  • 58
  • 53
  • 30
  • 26
  • 16
  • 13
  • 13
  • 7
  • 6
  • 1
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 23
    • 15
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    • 1
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    • 1
    • 1
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    • 1
    • 1
    C-Term

    原理

    GJB1 Antibody - C-terminal region

    序列

    GFGHRLSPEY KQNEINKLLS EQDGSLKDIL RRSPGTGAGL AEKSDRCSAC

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against GJB1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human GJB1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101322

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

  • 抗原

    GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

    别名

    GJB1

    背景

    Background Information: This gene encodes for a Connexin 32 protein. A large Charcot-Marie-Tooth disease family has been identified with a novel mutation in the Cx32 P2 promoter region at position -526bp. Cx32 mutants that are associated with a CNS phenotype may have toxic effects in oligodendrocytes.

    Gene Name: Gap junction protein, beta 1, 32 kDa

    Alternative Symbols: CMTX, CX32, CMTX1

    Protein Name: Gap junction beta-1 protein

    分子量

    31kDa

    基因ID

    2705

    NCBI登录号

    NP_000157

    UniProt

    P08034

    途径

    Cell-Cell Junction Organization
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