Recombinant Growth Hormone 1 抗体 (AA 58-187)
Quick Overview for Recombinant Growth Hormone 1 抗体 (AA 58-187) (ABIN6937317)
抗原
See all Growth Hormone 1 (GH1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 58-187
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特异性
- Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary)
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亚型
- IgG1 kappa
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anti-Growth Hormone 1 (GH1) antibody
GH1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GH-3155 unconjugated
anti-Growth Hormone 1 (GH1) (AA 28-217) antibodyGH1 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone 1 (GH1) (AA 58-187) antibodyGH1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GH-1371 unconjugated
anti-Growth Hormone 1 (GH1) (AA 1-217) antibodyGH1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3H1C2 unconjugated
anti-Growth Hormone 1 (GH1) (AA 28-216) antibodyGH1 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone 1 (GH1) (AA 1-217) antibodyGH1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G6 unconjugated
anti-Growth Hormone 1 (GH1) antibodyGH1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone 1 (GH1) (AA 28-216) antibodyGH1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone 1 (GH1) (AA 27-216) antibodyGH1 适用: 犬 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Pituitary cells. Human pituitary tissue (IHC).
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Growth Hormone 1 (GH1)
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别名
- GH1
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背景
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GH, GH-N, GH1, GHN, Growth hormone 1, Growth hormone, Growth hormone, pituitary, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, Somatotropin,Growth Hormone (Pituitary Marker)
Cellular localisation: Cytoplasmic -
分子量
- 20kDa
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基因ID
- 2688, 655229
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UniProt
- P01241
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途径
- NF-kappaB Signaling, JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
抗原
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