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Growth Hormone 1 抗体 (AA 58-187)

GH1 适用: 人 IHC, IHC (f) 宿主: 小鼠 Monoclonal GH-1371 unconjugated
产品编号 ABIN6937314
发货至: 中国
  • 抗原 See all Growth Hormone 1 (GH1) 抗体
    Growth Hormone 1 (GH1)
    抗原表位
    • 20
    • 13
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 58-187
    适用
    • 90
    • 17
    • 13
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    宿主
    • 64
    • 45
    • 1
    • 1
    小鼠
    克隆类型
    • 58
    • 53
    单克隆
    标记
    • 68
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Growth Hormone 1 antibody is un-conjugated
    应用范围
    • 66
    • 49
    • 31
    • 20
    • 19
    • 14
    • 14
    • 13
    • 13
    • 11
    • 9
    • 6
    • 5
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    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary)
    克隆位点
    GH-1371
    亚型
    IgG2b kappa
    Top Product
    Discover our top product GH1 Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Pituitary cells. Human pituitary tissue (IHC).

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Growth Hormone 1 (GH1)
    别名
    GH1 (GH1 产品)
    别名
    GH antibody, GH-N antibody, GHN antibody, IGHD1B antibody, hGH-N antibody, Gh1 antibody, GH1 antibody, gh antibody, Gh antibody, GH2 antibody, RNGHGP antibody, ghl antibody, gh-n antibody, ghn antibody, ighd1b antibody, gh1 antibody, ghb-A antibody, GHI antibody, GHB3 antibody, growth hormone 1 antibody, growth hormone antibody, somatotropin-like antibody, somatotropin antibody, growth hormone prepeptide antibody, growth hormone 1 L homeolog antibody, growth hormone 1 S homeolog antibody, Somatotropin-1 antibody, GH1 antibody, Gh antibody, GH antibody, LOC100305005 antibody, Gh1 antibody, LOC100534452 antibody, LOC100232594 antibody, LOC100303681 antibody, gh1 antibody, LOC100356068 antibody, LOC100136588 antibody, gh1.L antibody, gh1.S antibody, LOC109081196 antibody
    背景
    GH-N, GH1, Growth hormone 1, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, Somatotropin,Growth Hormone (Pituitary Marker)
    Cellular localisation: Cytoplasmic
    分子量
    20kDa
    基因ID
    2688, 655229
    UniProt
    P01241
    途径
    NF-kappaB Signaling, JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
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