FGF23 抗体
Quick Overview for FGF23 抗体 (ABIN6937228)
抗原
See all FGF23 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55 % amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human FGF23 protein
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亚型
- IgG1 kappa
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应用备注
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Known_Application: ELISA (For coating, order Ab without BSA), Functional Studies (Order Ab without BSA & Azide), Optimal dilution for a specific application should be determined.
Positive_Control: Human PBL cells. Brain tumors.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- FGF23 (Fibroblast Growth Factor 23 (FGF23))
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别名
- FGF23
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背景
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ADHR, FGF-23, FGFN, Fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, Tumor-derived hypophosphatemia-inducing factor,FGF23 (Fibroblast Growth Factor 23)
Cellular localisation: Secreted (extracellular) -
分子量
- 12-32kDa
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基因ID
- 8074, 287370
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UniProt
- Q9GZV9
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
抗原
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