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EGFR 抗体

EGFR 适用: 人 WB, IP 宿主: 小鼠 Monoclonal H9B4 unconjugated
产品编号 ABIN6937133
发货至: 中国
  • 抗原 See all EGFR 抗体
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This EGFR antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    This MAb reacts with a cytoplasmic domain of EGFR. EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin epiregulin.
    无交叉反应
    小鼠, 大鼠
    交叉反应 (详细)
    Human. Does not react with Mouse or Rat.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Purified EGFR from A431 cells.
    克隆位点
    H9B4
    亚型
    IgG1 kappa
    Top Product
    Discover our top product EGFR Primary Antibody
  • 应用备注

    Known_Application: Immunoprecipitation (1-2 μg/500 μg protein lysate), Western Blot (1-2 μg/mL for 2 hours at RT), Optimal dilution for a specific application should be determined.

    Positive_Control: A431 cells, Breast or Bladder cancer.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    别名
    EGFR (EGFR 产品)
    背景
    Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Receptor Tyrosine Protein Kinase, ErbB1, Urogastrone, wa2, Wa5,EGFR (Epidermal Growth Factor Receptor)
    Cellular localisation: Cell surface
    分子量
    ~170kDa (wild type) and ~145kDa (vIII variant)
    基因ID
    1956, 488293
    UniProt
    P00533
    途径
    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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