CD70 抗体
Quick Overview for CD70 抗体 (ABIN6936802)
抗原
See all CD70 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- It recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human CD70 protein
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亚型
- IgG1 kappa
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应用备注
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Known_Application: ELISA (For coating, order Ab without BSA), Functional Studies (Order Ab without Azide), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen) (1-2 μg/mL for 30 minutes at RT),Optimal dilution for a specific application should be determined.
Positive_Control: Raji cells. Lymph node or tonsil.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD70 (CD70 Molecule (CD70))
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别名
- CD70
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背景
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CD27 ligand (CD27L), CD27LG, Ki24, Surface antigen CD70, Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7),CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker)
Cellular localisation: Cell Surface -
分子量
- 30kDa
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基因ID
- 970, 501497, 715224
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UniProt
- P32970
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途径
- Cancer Immune Checkpoints
抗原
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