CD70 抗体
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北京 101111
Quick Overview for CD70 抗体 (ABIN6936801)
抗原
See all CD70 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- It recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown toinhibit T cell proliferation induced by dendritic cells.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Human WM-1 (Waldenstrom s macroglobulinemia) cell line
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亚型
- IgG1 kappa
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anti-CD70 Molecule (CD70) (AA 39-193) antibody
CD70 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) antibodyCD70 适用: 人 FACS 宿主: 小鼠 Monoclonal Ki-24 unconjugated
anti-CD70 Molecule (CD70) antibody (PE)CD70 适用: 人 FACS 宿主: 小鼠 Monoclonal Ki-24 PE
anti-CD70 Molecule (CD70) (AA 47-191) antibodyCD70 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) antibodyCD70 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) (AA 1-193) antibodyCD70 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) (AA 72-101) antibodyCD70 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) (AA 64-192) antibodyCD70 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) (AA 62-185) antibodyCD70 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order Ab without BSA), ,Inhibits T cell proliferation induced by dendritic cells (Order Ab without Azide), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunoprecipitation (1-2 μg/500 μg protein lysate), ,Immunohistochemistry (Frozen) (1-2 μg/mL for 30 minutes at RT),Optimal dilution for a specific application should be determined.
Positive_Control: Raji cells. Lymph node or tonsil.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD70 (CD70 Molecule (CD70))
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别名
- CD70
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背景
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CD27 ligand (CD27L), CD27LG, Ki24, Surface antigen CD70, Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7),CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker)
Cellular localisation: Cell Surface -
分子量
- 30kDa
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基因ID
- 970, 501497, 715224
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UniProt
- P32970
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途径
- Cancer Immune Checkpoints
抗原
-
