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CD40 抗体 (C-Term)

This anti-CD40 antibody is a 小鼠单克隆 antibody detecting CD40 in FACS 和 IF. Suitable for 人.

产品编号 ABIN6936710

发货至: 中国

Quick Overview for CD40 抗体 (C-Term) (ABIN6936710)

抗原

See all CD40 抗体

CD40

适用

216
118
25
19
8
6
6
5
4
3
2
2
2
2
1

人

宿主

小鼠

克隆类型

单克隆

标记

This CD40 antibody is un-conjugated

应用范围

196
100
73
64
46
34
28
23
20
16
14
13
11
5
5
4
4
4
4
4
3
3
3
2
2
2
1
1

Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

T8P2G4*A6

Discover our top product CD40 Primary Antibody

抗原表位
19

18

17

16

15

14

14

11

9

5

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term

特异性

This antibody is specific for the soluble form of CD40.It is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is expressed on B-lymphocytes, follicular dendritic cells, bone marrow-derived dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zones of secondary lymphoid organs.

交叉反应（详细）

Human.

纯化方法

1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

免疫原

Ovalbumin-conjugated synthetic peptide (RDPVCHPLGA) from the C-terminal of human CD40

亚型

IgG1 kappa
anti-CD40 (CD40) (AA 26-187) antibody
CD40 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD40 (CD40) antibody
CD40 适用: 人 FACS, IHC, IF, StM, DNA Mic 宿主: 小鼠 Monoclonal C40-1605 unconjugated

anti-CD40 (CD40) (AA 29-107) antibody
CD40 适用: 人 FACS, ELISA, IHC, StM, Coat 宿主: 小鼠 Monoclonal C40-2383 unconjugated

anti-CD40 (CD40) (C-Term) antibody
CD40 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD40 (CD40) (AA 21-193) antibody
CD40 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4C3B8 unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 适用: 人 FACS, IHC, St 宿主: 小鼠 Monoclonal 5C3 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD40 (CD40) antibody
CD40 适用: 人 FACS, IHC, IP, Act 宿主: 兔 Chimeric G28-5 unconjugated Recombinant Antibody

anti-CD40 (CD40) antibody
CD40 适用: 人 FACS 宿主: 小鼠 Monoclonal HI40a unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 适用: 人 FACS 宿主: 小鼠 Monoclonal HI40a FITC

应用备注

Known_Application: Immunofluorescence (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells)Optimal dilution for a specific application should be determined.
Positive_Control: L-428 cells. Tonsil, Spleen or Thymus.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

Prepared in 10 mM PBS, WITHOUT BSA and Azide.

储存液

Azide free

储存条件

-20 °C,-80 °C

储存方法

Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

有效期

24 months
抗原

CD40

别名

CD40

背景

B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, GP39, HIGM1, IGM, IMD3, p50, TBAM, TNF receptor superfamily member 5, TNFRSF5, TRAP,CD40 / TNFRSF5 / CD40L-Receptor
Cellular localisation: Cell Surface and Secreted

分子量

43kDa

基因ID

958, 472860

UniProt

P25942

途径

NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints

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