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CD3 epsilon 抗体 (AA 156-168)

This anti-CD3 epsilon antibody is a 兔 多克隆 antibody detecting CD3 epsilon in WB. Suitable for 人.
产品编号 ABIN6936698
发货至: 中国

Quick Overview for CD3 epsilon 抗体 (AA 156-168) (ABIN6936698)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

适用

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克隆类型

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多克隆

标记

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This CD3 epsilon antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 156-168

    特异性

    Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

    交叉反应 (详细)

    Human. Predicted to react with Ape, Orangutan, Gibbon, Chimpanzee, Monkey, Elephant, Horse, Cow, Sheep, Pig, Dog, Cat, Rabbit, Rat, Mouse, Guinea Pig, Hamster, Opossum, Frog, Chicken.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    A synthetic peptide aa156-168 (ERPPPVPNPDYEP) from human CD3e

    亚型

    IgG
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL for 60 minutes at RT), Optimal dilution for a specific application should be determined.

    Positive_Control: Jurkat cells. Tonsil and lymph node.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3E

    背景

    CD 3E, CD3 epsilon, CD3 TCR complex, CD3E, CD3e antigen epsilon polypeptide (TiT3 complex), T cell antigen receptor complex epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E, TCRE, TiT3 complex,CD3e (T-Cell Marker)
    Cellular localisation: Cell surface and cytoplasmic

    分子量

    20kDa

    基因ID

    916, 3003

    UniProt

    P07766

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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