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Recombinant CD27 抗体

CD27 适用: 人 FACS, IHC (f) 宿主: 小鼠 Monoclonal rLPFS2-1611 unconjugated Recombinant Antibody
产品编号 ABIN6936649
发货至: 中国
  • 抗原 See all CD27 抗体
    CD27 (CD27 Molecule (CD27))
    抗体类型
    Recombinant Antibody
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD27 antibody is un-conjugated
    应用范围
    • 137
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    Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant human CD22 protein (exact sequence is proprietary)
    克隆位点
    RLPFS2-1611
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD27 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Ramos cells. Human peripheral blood lymphocytes. Human tonsil and lymph node.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CD27 (CD27 Molecule (CD27))
    别名
    CD27 (CD27 产品)
    背景
    LPFS2, S152, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7,CD27 (Tumor Necrosis Factor Receptor Superfamily 7)
    Cellular localisation: Cell Surface
    分子量
    120kDa
    基因ID
    939, 355307
    UniProt
    P26842
    途径
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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