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CD27 抗体

This 小鼠 单克隆 antibody specifically detects CD27 in FACS 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN6936647
发货至: 中国
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北京 101111
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Quick Overview for CD27 抗体 (ABIN6936647)

抗原

See all CD27 抗体
CD27 (CD27 Molecule (CD27))

适用

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小鼠

克隆类型

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单克隆

标记

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This CD27 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

203-6
  • 原理

    CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody

    特异性

    Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27 (Workshop VI, Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

    交叉反应 (详细)

    Human.

    纯化方法

    200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.

    免疫原

    Sezary cells

    亚型

    IgG3, kappa
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: Human peripheral blood lymphocytes. Human tonsil and lymph node.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD27 (CD27 Molecule (CD27))

    别名

    CD27

    背景

    LPFS2, S152, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7

    Human peripheral blood lymphocytes. Human tonsil and lymph node.

    分子量

    120kDa

    基因ID

    939, 355307

    UniProt

    P26842

    途径

    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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