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CD1c 抗体

CD1C 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal CD1C-1603 unconjugated
产品编号 ABIN6936628
发货至: 中国
  • 抗原 See all CD1c (CD1C) 抗体
    CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
    适用
    • 46
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    宿主
    • 26
    • 19
    • 1
    小鼠
    克隆类型
    • 28
    • 18
    单克隆
    标记
    • 23
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    This CD1c antibody is un-conjugated
    应用范围
    • 27
    • 27
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
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    ELISA, Coating (Coat)
    特异性
    The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with -2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human CD1c protein
    克隆位点
    CD1C-1603
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD1C Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

    Positive_Control: Expressed on cortical thymocytes, on certain T-cell leukemias and in various other tissues.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
    别名
    CD1C (CD1C 产品)
    别名
    BDCA1 antibody, CD1 antibody, CD1A antibody, R7 antibody, CD1c molecule antibody, CD1C antibody
    背景
    BDCA1, CD1, CD1A, CD1c, CD1C antigen c polypeptide, CD1c molecule, Cortical thymocyte antigen CD1C, Differentiation antigen CD1 alpha 3, R7, T cell surface glycoprotein CD1c,CD1c
    Cellular localisation: Cell Surface
    分子量
    43kDa
    基因ID
    911, 132448
    UniProt
    P29017
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