BAP1 抗体 (AA 191-326)
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- 抗原 See all BAP1 抗体
- BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))
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抗原表位
- AA 191-326
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BAP1 antibody is un-conjugated
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应用范围
- ELISA, Coating (Coat)
- 特异性
- The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human BAP1 protein fragment (around aa 191-326) (exact sequence is proprietary)
- 克隆位点
- BAP1-2431
- 亚型
- IgG2c kappa
- Top Product
- Discover our top product BAP1 Primary Antibody
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- 应用备注
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Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat or PC-3 or HepG2 cells. Testis, Placenta, Ovarian or Breast Carcinoma.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))
- 别名
- BAP1 (BAP1 产品)
- 别名
- HUCEP-13 antibody, UCHL2 antibody, BAIAP3 antibody, 2300006C11Rik antibody, AA989761 antibody, AW553466 antibody, mKIAA0272 antibody, uch-x4 antibody, hucep-13 antibody, hucep-6 antibody, uchl2 antibody, si:dkey-42i9.9 antibody, BRCA1 associated protein 1 antibody, Brca1 associated protein 1 antibody, BRCA1 associated protein 1 L homeolog antibody, BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) antibody, BAP1 antibody, Bap1 antibody, bap1.L antibody, bap1 antibody
- 背景
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BAP1, BRCA1 associated protein 1, Cerebral protein 13, Cerebral protein 6, HUCEP 13, Hucep 6, HUCEP13, Hucep6, TPDS, Ubiquitin carboxy terminal hydrolase, Ubiquitin carboxyl terminal hydrolase BAP1, UCHL2,BAP1 (BRCA1 Associated Protein 1)
Cellular localisation: Nuclear and Cytoplasmic - 分子量
- 91kDa
- 基因ID
- 8314, 106674
- UniProt
- Q92560
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